RGUHS B.Pharm 4th Year 2020 Previous Question Papers - Rajiv Gandhi University of Health Sciences
Answer all questions. Be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
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LONG ESSAY (Answer any two) 2 X 10 = 20 Marks
- Enumerate anti-tubercular drugs with suitable examples. Outline the synthesis of Ethambutol, Isoniazid & Clofazamine
- Write a note on degradation of penicillin and give the chemistry and synthesis of chloramphenicol.
- Classify diuretics with examples. Give their clinical significance and mechanism of action of each class. Outline the synthesis of Acetazolamide.
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SHORT ESSAY (Answer any eight) 8 X 5 = 40 Marks
- Classify sulphonamides with suitable examples. Explain the SAR among antibacterial sulphonamides. Give the synthesis of sulfisoxazole.
- Outline the synthesis of Dapsone and Trimethoprim.
- Discuss the mechanism of action of alkylating agents. Write the structures of any two drugs.
- Write a note on Antiprotozoal agents. Outline the synthesis of metronidazole.
- Discuss the SAR of tetracyclines.
- Write a note on penicillinase resistant penicillins & Beta lactamase inhibitors.
- Explain with suitable examples (i) Anthelmintics and (ii) Antiviral agents
- Write the examples of hypoglycemic sulfonylureas and mention their specific uses. Give the synthesis of tolazamide.
- Classify preservatives with suitable examples and give the synthesis of Chlorobutanol.
- What are anti thyroid drugs? Name any two anti thyroid drugs and give their structures.
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SHORT ANSWERS 10 X 2 = 20 Marks
- Outline the mechanism of action of HMG CoA reductase inhibitors
- Name any two polypeptide antibiotics and give their uses:
- List out important antimalarial agents. Give the structure and use of any one antimalarial drug from natural source.
- Give the synthesis of Warfarin
- Give the synthesis of Gentian Violet.
- What are ACE inhibitors? Give two examples with structure.
- Explain the synergistic action of Amoxycillin and Clavulanic acid.
- Write short notes on Lincomycins
- Write briefly on potassium-sparing diuretics.
- Outline the synthesis of Mebendazole.
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